The carboxypeptidase A family can be divided into two subfamilies : carboxypeptidase H ( regulatory ) and carboxypeptidase A ( digestive ).
32.
David Cushman, Miguel Ondetti and colleagues used peptide analogues to study the structure of ACE, using carboxypeptidase A as a model.
33.
This would yield a coordination number of six for the zinc in the carboxypeptidase A-dipeptide glycyl-L-tyrosine complex.
34.
Although the primary sequence of CPVL bears every hallmarks of a serine carboxypeptidase, the enzymatic function of CPVL has not been confirmed.
35.
In fruit fly ( Drosophila melanogaster ), carboxypeptidase D is known as the silver mutation, with defects causing altered wing shape.
36.
Carboxypeptidase E is found in brain and throughout the neuroendocrine system, including the endocrine pancreas, pituitary, and adrenal gland chromaffin cells.
37.
This property of carboxypeptidase A led to the first clause of Daniel E . Koshland, Jr . s induced fit hypothesis.
38.
Several studies have been conducted exploring the details of the bond between carboxypeptidase A and substrate and how this affects the rate of hydrolysis.
39.
Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 ( CPA1 ) and expression is involved in the malignant progression of prostate cancer.
40.
However, this role for carboxypeptidase E remains controversial, and evidence shows that this enzyme is not necessary for the sorting of regulated secretory proteins.
