However it was later discovered that it was the only chymotrypsin-like elastase that was not expressed in the pancreas.
32.
KLK7 is a chymotrypsin-like serine protease, preferring to cleave proteins at the residues tyrosine, phenylalanine or leucine.
33.
:The C1 fragment must be the C terminus, because it ends in A which is not a chymotrypsin cleavage site.
34.
In addition to a C-terminal chymotrypsin-like serine protease domain, plasminogen contains an Kringle domains ( KR1-5 ).
35.
Later, Blow collaborated with Brian Hartley to solve the structure and explained the mechanism of chymotrypsin on the second enzyme structure to be solved.
36.
It is structurally unrelated to the chymotrypsin-clan of serine proteases, but uses the same type of catalytic triad in the active site.
37.
In brief, 20S sub complex presents three types proteolytic activities, including caspase-like, trypsin-like, and chymotrypsin-like activities.
38.
About half had abnormal levels of either calprotectin, a protein associated with gastrointestinal inflammation, or chymotrypsin, an enzyme released from the pancreas during digestion.
39.
The trypsin, once activated, can also cleave other trypsinogens as well as the precursors of other proteases such as chymotrypsin and carboxypeptidase to activate them.
40.
Literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B CELA3B ).
