Her research focuses on the role of organic cofactors as partners of enzymes catalyzing difficult biochemical reactions, especially folic acid and cobalamin ( vitamin B12 ).
32.
These may be supplemented, although since cyanocobalamin contains the toxic chemical cyanide, dogs that have serious cobalamin issues should instead be treated with hydroxocobalamin or methylcobalamin.
33.
The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis.
34.
Additionally, organic acid analysis or quantitative determination of methylmalonic acid should help to exclude cobalamin ( vitamin B12 ) defects and vitamin B12 deficiency giving a differential diagnosis.
35.
An abnormal result is caused by less of the labeled cobalamin to appear in the urine because it will remain in the intestine and be passed into the feces.
36.
The gene cluster controlling the biosynthesis of reuterin and cobalamin in the " L . reuteri " genome is a genomic island acquired from an anomalous source.
37.
Cobalamins are characterized by a porphyrin-like corrin nucleus that contains a single cobalt atom bound to a benzimidazolyl nucleotide and a variable residue ( R ) group.
38.
Patients of the " cblE " complementation group of disorders of folate / cobalamin metabolism which results in homocystinuria are defective in reductive activation of methionine synthase.
39.
One cause of elevated plasma B 12 ( cobalamin ) is general liver disease, since hepatic cytolysis releases B 12, and the affected liver shows decreased cobalamin clearance.
40.
One cause of elevated plasma B 12 ( cobalamin ) is general liver disease, since hepatic cytolysis releases B 12, and the affected liver shows decreased cobalamin clearance.
