| 31. | Prp8 has also been hypothesized to be a cofactor in RNA catalysis.
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| 32. | Macrocyclic ligands occur in many cofactors in proteins and enzymes.
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| 33. | Others require non-protein molecules called cofactors to be bound for activity.
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| 34. | For example, flavin and heme cofactors are often involved in redox reactions.
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| 35. | They require both AdoMet and Mg 2 + cofactors.
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| 36. | Some of the cofactors also require their own synthesis.
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| 37. | A magnesium ion is commonly used as a cofactor during the hydrolysis step.
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| 38. | Organic cofactors are often vitamins or made from vitamins.
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| 39. | In many cases, the cofactor includes both an inorganic and organic component.
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| 40. | Some 4Fe 4S clusters bind substrates and are thus classified as enzyme cofactors.
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