Dopamine increases myocardial contractility and cardiac output, without changing heart rate, by signaling through dopamine receptors.
32.
Phosphorylation of these channels increases their permeability to calcium and increases the contractility of their respective cardiac myocytes.
33.
Giallauria et al . describe the success of cardiac contractility modulation and the further potential of the therapy.
34.
This is caused by the terminally differentiated heart muscle fibers increasing in size in an attempt to improve contractility.
35.
Hypercalcemia can result in an increase in heart rate and a positive inotropic effect ( increase in contractility ).
36.
It has been reported that improvement in heart contractility has occurred as a result of the induction of angiogenesis.
37.
Coronary artery perfusion pressure is reduced in peripheral vasodilation, which results in reduced blood pressure and reduced myocardial contractility.
38.
Inhibition of these receptors prevents a response to the sympathetic nervous system, leading to decreased heart rate and contractility.
39.
Furthermore, nicardipine does not intrinsically decrease myocardial contractility and may be useful in the management of congestive heart failure.
40.
Hyperdynamic precordium can also be due to hyperthyroidism, and thus indicates an increased cardiac contractility, with systolic hypertension.
