Keratinization is the differentiation of keratinocytes in the stratum granulosum into nonvital surface cells or squames to form the stratum corneum.
32.
The permeability properties of the stratum corneum are, for the most part, unchanged after its removal from the body.
33.
Ultrastructural analysis has revealed tissue separation at the junction between the granular cells and the stratum corneum in the outer epidermis.
34.
But the stratum corneum is designed to keep out outside elements, such as bacteria, and is resistent to such invasions.
35.
But Prausnitz and Allen figured that very small needles could deliver vaccines and medication to the tissue just below the stratum corneum.
36.
Concomitantly, cells lose their nuclei and organelles causing the granular cells to become non-viable corneocytes in the stratum corneum.
37.
Below the epidermis lies the dermis, which is approximately one millimeter thick, 100 times the thickness of the stratum corneum.
38.
The lipids ultimately form the lamellar lipid bilayer that surrounds corneocytes and also contribute to permeability barrier homeostasis of the stratum corneum.
39.
Stratum corneum lipids are elaborately organized into lamellar structure, which plays the most important role for skin's barrier functions.
40.
While in preservation, the animal is of a pale lavender grey colour, with browner patches where stratum corneum is absent.
