He is known for the discovery of actinomycin, and the development of the industrial production by fermentation of many natural products, including cyanocobalamin, the avermectins, and other important antibiotics.
32.
"' Cyanocobalamin "'is one such form, i . e . " vitamer ", of B 12 because it can be metabolized in the body to an active coenzyme form.
33.
Since the cyanocobalamin form of B 12 is easy to crystallize and is not sensitive to air-oxidation, it is typically used as a form of B 12 for food additives and in many common multivitamins.
34.
The autopsy report indicates that abscesses on her buttocks ( presumably from prior injections of vitamin B12 in the form of cyanocobalamin, as well as human growth hormone ), and viral enteritis were contributory causes of death.
35.
In the serum, hydroxocobalamin and cyanocobalamin are believed to function as storage or transport forms of the molecule, whereas methylcobalamin and 5-deoxyadenosylcobalamin are the active forms of the coenzyme required for cell growth and replication.
36.
Treatment of megaloblastic anemia with concurrent vitamin deficiency using vitamers ( including cyanocobalamin ), creates the possibility of hypokalemia due to increased erythropoiesis ( red blood cell production ) and consequent cellular uptake of potassium upon anemia resolution.
37.
On close inspection it appears that nectar-feeding birds such as sunbirds rely on the ants and other insects that they find in flowers, not for a richer supply of protein, but for essential nutrients such as cyanocobalamin that are absent from nectar.
38.
Hydroxocobalamin is thought to be converted to the active enzymic forms of B 12 more easily than cyanocobalamin, and since it is little more expensive than cyanocobalamin, and has longer retention times in the body, has been used for vitamin replacement in situations where added reassurance of activity is desired.
39.
Hydroxocobalamin is thought to be converted to the active enzymic forms of B 12 more easily than cyanocobalamin, and since it is little more expensive than cyanocobalamin, and has longer retention times in the body, has been used for vitamin replacement in situations where added reassurance of activity is desired.
