| 31. | The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases.
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| 32. | The role of these highly conserved cysteines is not known.
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| 33. | Each of the periplasmic domains of the protein has two essential cysteines.
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| 34. | Cysteine 464 and histidine 414 are crucial for this activity.
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| 35. | Deficiency in MPST has been found related to mercaptolactate-cysteine disulfiduria.
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| 36. | Thus it is also considered to participate in cysteine degradation.
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| 37. | As a common feature no cysteines residues are present in this channel.
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| 38. | The C-terminal cysteine is depicted as ball and stick diagram.
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| 39. | It contains 4 conserved cysteine residues, which probably form disulphide bridges.
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| 40. | These four cysteines are involved in the binding of nickel.
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