The structure of 40-42 kDa porphobilinogen deaminase, which is highly conserved amongst organisms, consists of three domains.
32.
Biochemical analysis of A4 showed the lack of cytidine deaminase activity on single stranded DNA and it binds DNA rather weak.
33.
Tuberculosis pleural effusions can now be diagnosed accurately by increased levels of pleural fluid adenosine deaminase, above 40 U per liter.
34.
A3C was found to inhibit LINE-1 elements by directly interacting with ORF1p proteins, in a deaminase-indepedent manner.
35.
In 2002 this work led to the publication of the first successful gene therapy treatment for adenosine deaminase deficiency ( SCID ).
36.
This has already been investigated in a select few proteins such as adenosine deaminase, which acts on RNA ( ADAR ).
37.
Victims of the SCID disorder lack the gene that produces an enzyme known as adenosine deaminase, or " ADA ."
38.
The MIT scientists grew crystals of a stretch of Z-DNA tightly bound to the editing enzyme, called RNA adenosine deaminase.
39.
In 2002 this work led to the publication of the first successful gene therapy treatment for adenosine deaminase-deficiency ( SCID ).
40.
Patients with myoadenylate deaminase deficiency do not retain ribose during heavy exercise, so supplementation may be required to rebuild levels of ATP.
