| 31. | The pathological hallmark of ADEM is perivenular inflammation with limited   sleeves of demyelination .  .
 
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 | 32. | Demyelination may not even be directly caused by the virus, but by an unknown immune system response.
 
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 | 33. | Many conditions like demyelination and brain tumors can be ruled out by using magnetic resonance imaging ( MRI ).
 
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 | 34. | This then results in demyelination because of the buildup of sulfatide and is the main cause of Metachromatic Leukodystrophy.
 
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 | 35. | In certain demyelinating diseases CXCL12 has been shown to be decreased, possibly playing a role in demyelination failure.
 
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 | 36. | Cortical atrophy and demyelination along the subpial surface appear early in the disease course but accelerate in progressive stage.
 
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 | 37. | Depending on where the demyelination takes place and its severity, patients with tumefactive MS have different clinical symptoms.
 
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 | 38. | In the experiment, the two mice were conjoined and demyelination was induced via injection into the older mice.
 
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 | 39. | The experiment determined that factors from the younger mice reversed CNS demyelination in older mice by revitalizing the oligodendrocytes.
 
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 | 40. | Besides subpial demyelination suggest either a problem in the CSF or in the pia mater that should protect the cortex
 
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