The input of heat into an inherently endergonic reaction, such as the elimination of cyclohexanol to cyclohexene, can be seen as coupling an unfavourable reaction ( elimination ) to a favourable one ( burning of coal or other provision of heat ) such that the total entropy change of the universe is greater than or equal to zero, making the " total"
32.
The energy released by this highly exergonic oxidation reaction drives the endergonic second reaction ( ?G?= + 50 kJ / mol ( + 12kcal / mol ) ), in which a molecule of inorganic phosphate is transferred to the GAP intermediate to form a product with high phosphoryl-transfer potential : "'1, 3-bisphosphoglycerate "'( 1, 3-BPG ).
33.
A favorable reaction is one in which the change in free energy " G?is negative ( exergonic ) or in other words, the free energy of product, G?product, is less than the free energy of the starting materials, G?reactant . " G?> 0 ( endergonic ) corresponds to an unfavorable reaction . " G?can be written as a function of change in enthalpy ( " H?) and change in entropy ( " S?) as "' " G?= " H?T " S?" '.
