See ubiquitination, proteasome, autophagy, endosome, lysosome . . . no doubt I'm forgetting lots of biggies.
32.
The second two involve the full fusion of the vesicle with the membrane, followed by recycling, or recycling into the endosome.
33.
Below a pH of 6.0 ( the pH in an endosome ), both LF and EF become disordered molten globules.
34.
The dropping pH inside the endosome frees the outer domain of E1 and causes the fusion of the viral envelope with the endosomal membrane.
35.
The sequential stages of HSV entry are analogous to endocytosed after binding to the receptors, and the fusion could occur at the endosome.
36.
The endosome is moved to the Golgi apparatus, where the A1 protein is recognized by the endoplasmic reticulum chaperon, protein disulfide isomerase.
37.
TRPML1 is believed to channel iron ions across the endosome / lysosome membrane into the cell and so its malfunction causes cellular iron deficiency.
38.
The cellular membrane pinches in a procession known as pinocytosis and allows entry of the virus into the cell by way of an endosome.
39.
The believed mechanism for this has to do with an acidification of the endosome, similar to what is done in the influenza virus.
40.
The low pH within the endosome then triggers BTV's membrane penetration protein VP5 to undergo a conformational change that disrupts the endosomal membrane.
