Korsakoff's involves neuronal loss, that is, damage to neurons; gliosis, which is a result of damage to supporting cells of the central nervous system, and hemorrhage or bleeding also occurs in dorsomedial nucleus or anterior group of the thalamus ( limbic-specific nuclei ) is also associated with this disorder.
32.
It is important to differentiate PVL from the following major white matter lesions in the cerebral hemispheres : edematous hemorrhagic leukoencephalopathy ( OGL ), telentsefalny gliosis ( TG ), diffuse leukomalacia ( DFL ), subcortical leukomalacia ( SL ), periventricular hemorrhagic infarction ( PHI ), intracerebral hemorrhage ( ICH ), multicystic encephalomalacia ( ME ), subendymal pseudocyst.
33.
Activated astrocytes form the major component of the encapsulating tissue that forms around implanted electrodes . " Current theories hold that glial encapsulation, i . e . gliosis, insulates the electrode from nearby neurons, thereby hindering diffusion and increasing impedance, extends the distance between the electrode and its nearest target neurons, or creates an inhibitory environment for neurite extension, thus repelling regenerating neural processes away from recording sites " .
34.
These include : the inclusions seen in nerve cells ( Pick bodies ) characteristic of Pick s disease; nerve cell loss in the cerebral cortex and basal ganglia seen in Corticobasal Degeneration; and Dementia Lacking Distinctive Histopathology ( DLDH ), which is a pattern of neural damage seen in several types of FTD . DLDH is characterized by neuronal loss, gliosis ( overgrowth, or development of tumors ), and spongiosis ( swelling with excess fluid ).
