| 31. | Plasmepsins I and II cleave hemoglobin between residues Phenylalanine 33 and Leucine 34 of ?-globin subunit.
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| 32. | Usually there are four genes that code for alpha globin and two genes that code for beta globin.
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| 33. | Usually there are four genes that code for alpha globin and two genes that code for beta globin.
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| 34. | The CoTC core is highly conserved in the 3'UTR of other primate beta-globin genes.
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| 35. | Both of these globins contain an virginal prosthetic group for binding oxygen and they contain many similar structural characteristics.
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| 36. | GATA1 was first described as a red blood cell lineage transcription factor that activates the beta-globin gene.
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| 37. | Hb H usually occurs in some alpha thalassemia and is composed of four beta globin ( protein ) chains.
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| 38. | Some mutations in the globin chain are associated with the hemoglobinopathies, such as sickle-cell disease and thalassemia.
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| 39. | Thalassemias, in contrast, usually result in underproduction of normal globin proteins, often through mutations in regulatory genes.
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| 40. | Bacteria have all three types of globins, while archaea lack flavohaemoglobins, and eukaryotes lack globin-coupled sensors.
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