Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn reduces hydrogen peroxide ( H2O2 ), a dangerously reactive species within the cell.
32.
The antioxidant enzyme glutathione peroxidase 4 ( GPx4 ) belongs to the family of glutathione peroxidases, which consists of 8 known mammalian isoenzymes ( GPx1-8 ).
33.
In one study, the activity of glutathione peroxidase along with other antioxidant enzymes such as superoxide dismutase and catalase was not associated with coronary heart disease risk in women.
34.
It performs its functions as antioxidant in the glutathione peroxidase pathway, and it protects cell membranes from oxidation by reacting with lipid radicals produced in the lipid peroxidation chain reaction.
35.
Shukla, V . K . S .; Srivastava, K . C . : Erythrocyte glutathione peroxidase and serum lipid pattern : A comparison between Indian immigrants and Danes.
36.
Glutathione peroxidase ( GPx ) activity was significantly higher in the DOW group than in the control group, while there was no difference between the surface seawater and control groups.
37.
This is in line with findings showing that ?-tocopherol, but not water-soluble antioxidants, efficiently protects glutathione peroxidase 4 ( GPX4 )-deficient cells from cell death.
38.
Mice genetically engineered to lack glutathione peroxidase 1 ( Gpx1 " / " mice ) are grossly phenotypically normal and have normal lifespans, indicating this enzyme is not critical for life.
39.
The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products.
40.
Glutathione peroxidase 1 is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine ( Ala ) repeats in this sequence.
