Several recent colon cancer screening guidelines have recommended replacing any older low-sensitivity, guaiac-based fecal occult blood testing ( gFOBT ) with either newer high-sensitivity guaiac-based fecal occult blood testing ( gFOBT ) or fecal immunochemical testing ( FIT ), which tests for globin rather than the heme detected by the guaiac method.
32.
Several recent colon cancer screening guidelines have recommended replacing any older low-sensitivity, guaiac-based fecal occult blood testing ( gFOBT ) with either newer high-sensitivity guaiac-based fecal occult blood testing ( gFOBT ) or fecal immunochemical testing ( FIT ), which tests for globin rather than the heme detected by the guaiac method.
33.
FIT screening is more effective in terms of health outcomes and cost compared with guaiac FOBT . According to the guidelines of the American College of Gastroenterology, " Annual fecal immunochemical testing is the preferred colorectal cancer detection test . " A FIT test detects globin levels in feces at or above 50 nanograms per mL, the established cutoff by the World Health Organization for Colorectal Cancer Screening.
