This depends on the state of the particle and, in some implementation, on the states of its neighbours in a holoenzyme or complex.
32.
BRCA1 was shown to co-purify with the human RNA Polymerase II holoenzyme in HeLa extracts, implying it is a component of the holoenzyme.
33.
BRCA1 was shown to co-purify with the human RNA Polymerase II holoenzyme in HeLa extracts, implying it is a component of the holoenzyme.
34.
Part of the assembly of the holoenzyme is referred to as the mediator complex acts as a bridge between RNA polymerase II and the transcription factors.
35.
The monomers then associate into homodimers, and bind AdoCbl ( one for each monomer active site ) to form the final, active holoenzyme form.
36.
The "'beta clamp "'is a specific DNA clamp and a subunit of the DNA polymerase III holoenzyme found in bacteria.
37.
In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction.
38.
DNA Pol I can also be characterized as having core and holoenzyme segments, where the 5'exonuclease can be removed without destroying enzyme functionality.
39.
The DNA Pol? holoenzyme is often considered to include PCNA and RFC as well as the four subunits of the polymerase complex ( Figure 1 ).
40.
CAPPs can be present as the core dimeric enzyme of AC or a trimeric holoenzyme of ABC or AB C ( Janssens & Goris, 2001 ).