The reaction sequence is also stereoselective, giving syn addition ( on the same face of the alkene ) : the hydroboration is syn-selective and the oxidation replaces the boron with hydroxyl having the same geometric position.
32.
These include the application of CGCs as catalysts for hydrogenation of imines, hydroboration of alkenes, carboalumination of alkenes, hydrosilylation of alkenes, hydroamination / cyclisation of alpha, omega-aminoalkenes and dimerisation of terminal alkynes.
33.
For the ?, ? unsaturated systems "'10 "'- "'12 "', efficient reduction of the ketone occurs despite the possible side reaction of hydroboration of the C-C unsaturated bond.
34.
In chemistry, "'hydroboration "'refers to the addition of a hydrogen-boron bond to C-C, C-N, and C-O double bonds, as well as C-C triple bonds.
35.
Zweifel G, Najafi MR, Rajagopalan S . " Hydroboration of Methoxyenynes : A Novel Synthesis of ( E )-Methoxyenones " Tetrahedron Lett 1988; 29 : 1895 . doi : 10.1016 / S0040-4039 ( 00 ) 82071-7.
36.
Hydroboration of 1, 2-disubstituted alkenes, such as a " cis " or " trans " olefin, produces generally a mixture of the two organoboranes of comparable amounts, even if the substituents are very different in terms of steric bulk.
