In 1971, Knoll showed that selegiline selectively inhibits the B-isoform of monoamine oxidase ( MAO-B ) and proposed that it is unlikely to cause the infamous " cheese effect " ( hypertensive crisis resulting from consuming foods containing tyramine ) that occurs with non-selective MAO inhibitors.
32.
While safer than general MAOIs, RIMAs still have highly dangerous and sometimes fatal interactions with many common drugs; in particular, they can cause serotonin syndrome or hypertensive crisis when combined with almost any antidepressant or stimulant, common migraine medications, certain herbs, or even most cold medicines ( including decongestants, antihistamines, and cough syrup ).
33.
Olga Capablanca recalled that his high blood pressure nearly cost him his life : " A doctor screamed at me,'How could you let him play ?'" In a later interview Capablanca denied having a systolic / 180 diastolic ( hypertensive crisis is 180 / 120 or above, and even after treatment Capablanca had 180 / 130 ).
34.
For example, the diet followed by shamans and apprentices prior to participating in an ayahuasca ceremony includes foods rich in tryptophan ( a biosynthetic precursor to serotonin ) as well as avoiding foods rich in tyramine, which could induce hypertensive crisis if ingested with MAOIs such as are found in ayahuasca brews as well as abstinence from alcohol or sex.
