The Apnea-Hypopnea Index ( AHI ), the number of breathing obstructions or near-obstructions per hour of sleep, is one common way to measure the degree of a patient's sleep apnea.
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The direct consequence of hypopnea ( as well as apnea ) is that the CO 2 in the blood increases and the oxygen level in the patient s blood decrease is proportionate to the severity of the airway obstruction.
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The term " sleep-disordered breathing " is commonly used in the U . S . to describe the full range of breathing problems during sleep in which not enough air reaches the lungs ( hypopnea and apnea ).
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A RERA is characterized by increasing respiratory effort ( and thus decreasing esophageal pressures ) for 10 seconds or more leading to an arousal from sleep, but one that does not fulfill the criteria for a hypopnea or apnea.
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The distinction lies in what is observed at the trough of ventilation : Cheyne Stokes respiration involves apnea ( since apnea is a prominent feature in their original description ) while periodic breathing involves hypopnea ( abnormally small but not absent breaths ).
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With moderate to severe hypopnea, sleep is disturbed such that patients may get a full night's sleep but still not feel rested because they did not get the blood oxygen level, which may in turn disrupt the stages of sleep.
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The company said the panel's recommendation was based on positive results from several clinical studies showing the safety and effectiveness of the drug in patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea / hypopnea syndrome and shift-work sleep disorder.
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The respiratory disturbance index is similar to the apnea-hypopnea index; however, it also includes respiratory events that do not technically meet the definitions of apneas or hypopneas, such as a Respiratory Effort Related Arousal ( RERA ), but do disrupt sleep.
39.
The respiratory disturbance index is similar to the apnea-hypopnea index; however, it also includes respiratory events that do not technically meet the definitions of apneas or hypopneas, such as a Respiratory Effort Related Arousal ( RERA ), but do disrupt sleep.
40.
During the first 71 minutes of sleep Mr . B _ _ _ _ manifested 83 obstructive apneas, 3 central apneas, 1 mixed apnea and 28 hypopneas, for an elevated apnea + hypopnea index ( AHI ) of 97 events / hr ( * " severe " OSA ).
