Alternately, the pyrolysis can be performed in solution, allowing a one-pot reaction with chemicals already present rather than isolating the unstable ketene intermediate.
32.
Because it is a dimer, it shares an empirical formula with CO . It can be thought of as ketene of glyoxylic acid ( OHCCOOH ).
33.
Cyclobutenone was originally synthesized from the 3-bromocyclobutanone and 3-chlorocyclobutanone precursors which were prepared from an allene and a ketene via two independent routes.
34.
In the exposed regions, the DNQ forms a ketene, which, in turn, reacts with ambient water to form a base soluble indene carboxylic acid.
35.
A Wolff Rearrangement of the diazoacetoacetate enone ( pink ) forms a stable ketene, which reacts with the imine to form a stable ?-lactam compound.
36.
In these contexts, it appears that the carbonite ion reacts with excess carbon monoxide to form an anion with the ketene structure, O = C =.
37.
The tertiary amine contained within the quinuclidine can act as a nucleophile that attacks the most electrophilic carbon of the ketene to promote the formation of ?-lactams.
38.
The greatest use of thermal Wolff rearrangements is the formation of carboxylic acid analogs, by interception of the ketene with high boiling solvents, such as aniline and phenol.
39.
The use of 2-chloroacrylonitrile as dienophile is a viable synthetic equivalent for ketene, Hydrolysis of the epimeric mixture of chloronitrile adducts revealed the desired bicycloheptanone in high yield.
40.
In the proposed reaction mechanism the base first converts the acid chloride to the ketene, the organocatalyst then introduces chirality through its quininoid tertiary amine, forming a ketene adduct.
