Death by CO ( or any gas ) doesn't require a hermetic seal-it only requires an input rate higher than the output rate, for long enough to get to the lethal concentration of CO . talk ) 22 : 07, 26 January 2015 ( UTC)
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"' Fish acute toxicity syndrome "'( FATS ) is a set of common chemical and functional responses in fish resulting from a short-term, acute exposure to a lethal concentration of a toxicant, a chemical or material that can produce an unfavorable effect in a living organism.
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:: : : The CO in engine exhaust, if it escapes before reaching a catalytic converter, is 20-50 times the minimum lethal concentration, so you wouldn't need that much of a leak to start causing problems . talk ) 02 : 48, 27 January 2015 ( UTC)
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According to the National Institute of Health, " No reports of human poisoning cases found; Causes seizures and liver injury in animal studies; At lethal concentrations, inhalation causes excitement, somnolence, muscle contractions, and fatty liver degeneration in mice; Causes convulsions in rats after feeding lethal doses; ", and it is " highly toxic by inhalation; Effects in high-dose animal studies include convulsions ."
