In human liver microsomes, cytochrome P450-mediated styrene oxidation showed the production of more " S " enantiomer relative to the " R " enantiomer.
32.
The "'microsomal ethanol oxidizing system "'( MEOS ) is an alternate pathway of ethanol metabolism that occurs in the microsome in the oxidation of ethanol to acetaldehyde.
33.
The loss of cytochrome P-450 and monooxygenase activity seen on incubation of liver microsomes with ANTU is likely the result of the covalent binding of atomic sulfur to cytochrome P-450.
34.
Some lots are available to study specific populations ( example : lung microsomes from smokers or non-smokers ) or divided into classifications to meet target CYP activity levels for inhibition and metabolism studies.
35.
Within the cell, GGT is located in microsomes and along the biliary tract plasma membrane, GGT is more commonly measured than 5-NT because GGT testing is widely available on a variety of laboratory instruments.
36.
In contrast to these finding from rat liver microsomes, mammalian acyl transferase from dog lungs was found to exhibit no preference between 1-lyso-2-acyl-phosphatidylcholine and 1-acyl-2-lyso-phosphatidylcholine.
37.
A subset of Cytochrome P450 ( CYP450 ) microsome-bound ?-hydroxylases ( see 20-Hydroxyeicosatetraenoic acid ) metabolize arachidonic acid to 20-Hydroxyeicosatetraenoic acid ( 20-HETE ) and 19-hydroxyeicosatetraenoic acid by an omega oxidation reaction.
38.
It is metabolized in human hepatocytes and human microsomes to form [ 2-( 2', 6'- dichloro-4'- hydroxy-phenylamino ) phenyl ] acetoxyacetic acid as the major metabolite, which is then further conjugated.
39.
The C-hydroxylated metabolites may be considered as the detoxication products, while the benzenediazonium ion ( BDI ) formed by microsome-catalyzed enzymatic splitting of the azo group of Sudan I, reacts with DNA " in vitro > ".
40.
The expression of CYP1A1 in human livers is low, less than 0, 7 % of the total hepatic CYP expression, while it contributes up to 12 to 30 % in the oxidation of Sudan I in a set of human liver microsomes.
