Typical applications for this design of microtome are of the preparation of large samples, such as those embedded in paraffin for biological preparations.
32.
For larger pieces of tissue, thin sections ( slices ) are made using a microtome; these slices can then be mounted and inspected.
33.
Alternately this design of microtome can also be used for very hard materials, such as bones or teeth, as well as some ceramics.
34.
These instruments are similar to the microtome, but the speed and vibration ( or oscillation frequency ) of the cutting blade can be controlled.
35.
The deeper layers, if reshaped by a laser or cut by a microtome, will remain that way permanently with only limited healing or remodelling.
36.
In the laser microtome the laser-microdissection of internal areas in tissues, cellular structures, and other types of small features is also possible.
37.
Designed between 1884 / 85, The rocking microtome was one of Darwin's most successful designs which continued to be manufactured until the 1970s.
38.
The company also produced photographic lenses ( 1883 ), spectacle lenses ( 1889 ), microtomes ( 1890 ), binoculars and telescopes ( 1893 ).
39.
A sledge microtome is a device where the sample is placed into a fixed holder ( shuttle ), which then moves backwards and forwards across a knife.
40.
For the cutting of frozen samples, many rotary microtomes can be adapted to cut in a liquid-nitrogen chamber, in a so-called cryomicrotome setup.
