Heart murmurs may indicate the presence of valvular heart disease, either as a cause ( e . g . aortic stenosis ) or as a result ( e . g . mitral regurgitation ) of the heart failure.
32.
Braunwald designed and fabricated experimental artificial mitral valve prostheses, implanting them in dogs at the National Heart Institute's surgical clinic in 1959 . On 11 March 1960, the first successful human implant followed, in a 44-year-old woman with mitral regurgitation.
33.
In a study of people with heart valve regurgitation that compared measurements 2 weeks apart for each person, there was an increased severity of aortic and mitral regurgitation when diastolic blood pressure increased, whereas when diastolic blood pressure decreased, there was a decreased severity.
34.
Electrocardiography may show " P mitrale ", that is, broad, notched P waves in several or many leads with a prominent late negative component to the P wave in lead V 1, and may also be seen in mitral regurgitation, and, potentially, any cause of overload of the left atrium.
35.
However, he has continued to experience shortness of breath because of mitral regurgitation, and Shands doctors, in consultation with colleagues around the country, recommended Monday's surgical procedure, which is scheduled to take place at a hospital in the Northeast that the family chose not to specify _ other than to say it is not in Boston.
