| 31. | Westheimer et al .'s proposal was further supported by site-directed mutagenesis studies.
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| 32. | His cloning vectors were also used to develop the method for oligonucleotide site-directed mutagenesis.
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| 33. | The development of microbial genome sequencing was a major advance for the use of transposon mutagenesis.
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| 34. | In addition, random germline mutagenesis with ENU has been used to decipher the TLR signaling pathways.
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| 35. | Protein-protein interactions can be quantitatively analyzed for structural variations resulted from site-directed mutagenesis.
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| 36. | In a study, they used targeted mutagenesis in mice to delete Tbx2 locus in some specimen.
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| 37. | This technology, known as insertion mutagenesis, often employs retroviruses as the vectors of DNA delivery.
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| 38. | Such insertion mutagenesis has been often used to identify many oncogenes in specific locations in tumor cells.
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| 39. | The structure was confirmed by mutagenesis and has an NMR and mass spectrometric detection ( MS3D ).
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| 40. | Thus, ROS production in the stroma fuels cancer cell evolution via a process of random mutagenesis.
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