Neuroblasts are the progenitor cells which divide asymmetrically to give rise to another neuroblast and a ganglion mother cell ( GMC ).
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However, there is some controversy in the terminology because virtually any malformation will involve neuroblast migration, either primarily or secondarily.
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Once the future neuroblast cells are selected, they delaminate, then carry on dividing for a pre-programmed number of divisions.
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He successfully cultured frog neuroblasts in a lymph medium and thereby took the first step toward current research on precursor and stem cells.
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It is equally distributed throughout the neuroblast cytoplasm, but becomes localized at the basal cortex when the neuroblast starts to undergo mitosis.
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It is equally distributed throughout the neuroblast cytoplasm, but becomes localized at the basal cortex when the neuroblast starts to undergo mitosis.
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Undifferentiated neuroblasts may show enlarged and vesicular nuclei with thick nuclear membranes and prominent nucleoli, often a clue to forthcoming anaplastic change.
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From there, one particular cell from each cluster is selected to become a neuroblast, through the action of the Notch signaling pathway.
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It is expressed in neuroblasts, but is kept out of the nucleus by Miranda, which tethers it to the cell basal cortex.
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The same researchers have turned scar-forming astrocytes into progenitor cells called neuroblasts that regenerated into neurons in the injured adult spinal cord.
