The CB 1 receptor is expressed pre-synaptically at both glutaminergic and GABAergic interneurons and, in effect, acts as a neuromodulator to inhibit release of glutamate and GABA . Repeated administration of receptor agonists may result in receptor internalization and / or a reduction in receptor protein signalling.
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Surgical ( invasive ) facial rejuvenation procedures can include a brow lift ( forehead lift ), eye lift ( blepharoplasty ), facelift ( rhytidectomy ), chin lift and neck lift . Non-surgical ( non-invasive ) facial rejuvenation treatments can include chemical peels, neuromodulator ( such as botox ), dermal fillers, laser resurfacing, photorejuvenation, radiofrequency and Ultrasound.
