He used diluted plasma or serum as the perfusate and pointed out the necessity for low perfusate pressures to prevent kidney swelling, but admitted that the optimum values for such variables as perfusate temperature, Po2, and flow, remained unknown.
32.
An analysis of the control quality characteristic oscillations caused by the varying of the parameters makes it possible to figure out if the parameters have optimum values, i . e . . if those values deliver extreme ( minimum or maximum ) values of the control quality characteristic.
33.
The basic principle that underlies homeostasis is negative feedback : any time a parameter diverges from its set-point, sensors generate an error signal that evokes a response that causes the parameter to shift back toward its optimum value . ( This principle is widely used in engineering, for example in the control of temperature using a thermostat .)
34.
:: : : The problem with interpreting the historical Laffer Curve is that it is independent of the Gini coefficient-- if you plot tax rates and the Gini score as the independent variables, their effect on growth is much clearer . "'This suggests a way to find the optimum values . "'talk ) 12 : 55, 27 March 2010 ( UTC)
35.
When the object is three-dimensional, the optimum rotation is represented by a 3-by-3 rotation matrix " R ", rather than a simple angle, and in this case singular value decomposition can be used to find the optimum value for " R " ( see the solution for the constrained orthogonal Procrustes problem, subject to det ( " R " ) = 1 ).
