A sinusoidal pressure wave results in localized vibrations of the organ of Corti : near the base for high frequencies, near the apex for low frequencies.
32.
By phylogenetic analysis, pendrin has been found to be a close relative of prestin present on the hair cells or organ of corti in the inner ear.
33.
Though this may seem to be a positive development, Rb-knockdown mice tend to develop severe hearing loss due to degeneration of the organ of Corti.
34.
In fact, when the CDKN1B gene is disrupted in adult mice, hair cells of the organ of Corti proliferate, while those in control mice do not.
35.
In such a model, a lop sided pressure about the Organ of Corti is hypothesized which actively adds to the passive traveling wave to form the active traveling wave.
36.
Two of the three fluid sections are canals and the third is a sensitive'organ of Corti'which detects pressure impulses which travel along the auditory nerve to the brain.
37.
If the mother is infected with rubella during the ninth week, a crucial week for internal ear development, there can be destruction of the organ of Corti, causing deafness.
38.
The hair cells in the organ of Corti are tuned to certain sound frequencies by way of their location in the cochlea, due to the degree of stiffness in the basilar membrane.
39.
It is the inner hair cells of the organ of Corti that are responsible for activation of afferent receptors in response to pressure waves reaching the basilar membrane through the transduction of sound.
40.
Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti.
