More detail was given in Darwin's 1868 book on " The Variation of Animals and Plants under Domestication ", which tried to explain heredity through his hypothesis of pangenesis.
32.
An interesting attribute of this idea is that it strongly resembles Darwin's own theory of pangenesis, except in the soma to germ line feedback theory, pangenes are replaced with realistic retroviruses.
33.
A large proportion of the book contains detailed information on the domestication of animals and plants but it also contains in Chapter XXVII a description of Darwin's theory of heredity which he called pangenesis.
34.
The pangenesis theory, similar to Hippocrates's views on the topic, imply that the whole of parental organisms participate in heredity ( thus the prefix " pan " ) while adapting to cell theory.
35.
Galton was troubled because he began the work in good faith, intending to prove Darwin right; and he praised pangenesis in " Hereditary Genius " in 1869 . Somehow he had unintentionally proved Darwin wrong.
36.
Specifically, in 1889, Hugo de Vries published his book " Intracellular Pangenesis ", in which he postulated that different characters have individual hereditary carriers and that inheritance of specific traits in organisms comes in particles.
37.
Some Lamarckian principles, however, have not been entirely discounted and some of Darwin's pangenesis principles ( in this regard ) do relate to heritable aspects of phenotypic plasticity, while the status of gemmules has been firmly rejected.
38.
Darwin's book " The Variation of Animals and Plants under Domestication " ( 1868 ) was the first part of his planned " big book ", and included his unsuccessful hypothesis of pangenesis attempting to explain heredity.
39.
Responding to Fleming Jenkin's review of " On the Origin of Species ", he argued that pangenesis would permit the preservation of some favourable variations in a population so that they wouldn't die out through blending.
40.
Darwin's hypothesis of pangenesis, while relying in part on the inheritance of acquired characteristics, proved to be useful for statistical models of evolution that were developed by his cousin Francis Galton and the " biometric " school of evolutionary thought.
