"' Glutarimide "'is a chemical compound featuring a piperidine ring with two ketones attached next to the nitrogen.
32.
"' Piperidine "'is an organic compound with the molecular formula ( CH 2 ) 5 NH . This pepper.
33.
The synthesis is the same as for phenadoxone, with the exception that piperidine is used " in lieu " of morpholine.
34.
Using this strategy, Fowler and coworkers were able to use the 1-aza-Cope rearrangement to create piperidine and pyridine derivatives.
35.
With other amines such as piperidine the ring-opened compound after loss of hydrogen bromide to the nitrile is also the isolated reaction product:
36.
"' Stenusin "'is a piperidine alkaloid molecule synthesized by rove beetles of the genus " Stenus Latreille ".
37.
Ziering and Lee found that embellishing this structure via the incorporation of a 3-methyl group into the piperidine nucleus greatly enhanced the pharmacological activity.
38.
Many of the piperidine analogues of cocaine serve as the'missing link'between the cocaine structure and that of the methylphenidate class of drugs.
39.
The first attempt of laboratory synthesis was made by German chemist Hans Meerwein in 1924 using reaction of formaldehyde with diethyl malonate in the presence of piperidine.
40.
Unlike the pethidine & prodine classes of opioid, the N-allyl homologue of ketobemidone shows antagonist properties as do derivatives substituted on the piperidine ring.
