Beyond this, it improves cardiac contractility, coronary artery blood flow, metabolism of carbohydrates, and decreases platelet aggregation and plaque formation.
32.
Failure to express the FERMT3 protein disrupts the ability to form clots and coagulate by preventing integrin ?II?3-mediated platelet aggregation.
33.
Testosterone also regulates the population of thromboxane A 2 receptors on megakaryocytes and platelets and hence platelet aggregation in humans.
34.
Because thromboxanes play a role in vasoconstriction and platelet aggregation, their dominance can disrupt vascular homeostasis and cause thrombotic vascular events.
35.
Platelet aggregation is achieved by mediating expression of the glycoprotein complex GP IIb / IIIa in the cell membrane of platelets.
36.
It is an antimitotic agent and shows weak inhibitory activity of blood platelet aggregation induced by simulation of the central nervous system.
37.
Especially the degradation of fibrinogen, an essential protein for platelet aggregation and clot stability, may be a major cause for clinical bleeding.
38.
"' Triflusal "'is a platelet aggregation inhibitor that was discovered and developed in the Uriach Laboratories, and commercialised in Spain since 1981.
39.
It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane.
40.
Vane and a team from the Wellcome Foundation had identified a lipid mediator they called PG-X, which inhibited platelet aggregation.
