Polymyxins B are not absorbed from the gastrointestinal tract, so another route of administration must be chosen, e . g ., parenteral ( often intravenously ) or by inhalation.
32.
All the isolates were resistant to multiple different classes of antibiotics, including beta-lactam antibiotics, fluoroquinolones, and aminoglycosides, but most were still susceptible to the polymyxin antibiotic colistin.
33.
Some antibiotics require monitoring to balance efficacy with minimizing adverse effects, including : gentamicin, vancomycin, amphotericin B ( nicknamed'amphoterrible'for this very reason ), and polymyxin B.
34.
Topical use of 0.1 % propamidine isethionate ( Brolene ) plus neomycin-polymyxin B-gramicidin ophthalmic solution has been a successful approach; keratoplasty is often necessary in severe infections.
35.
The initial choice of antibiotic depends upon personal choice, experience and availability, but could include chloramphenicol, chlortetracycline, bacitracin-neomycin-polymyxin ( BNP ), ciprofloxacin, ofloxacin and tobramycin.
36.
Each mL Contains : ACTIVES : Polymyxin B Sulfate equal to 10, 000 polymyxin B units, Trimethoprim Sulfate ( equivalent to trimethoprim 1 mg ); INACTIVES : Purified Water, Sodium Chloride.
37.
Each mL Contains : ACTIVES : Polymyxin B Sulfate equal to 10, 000 polymyxin B units, Trimethoprim Sulfate ( equivalent to trimethoprim 1 mg ); INACTIVES : Purified Water, Sodium Chloride.
38.
By increasing permeability of the bacterial membrane system, polymyxin is also used in clinical work to increase release of secreted toxins, such as " Shiga " toxin from " Escherichia coli ".
39.
OFPBL contains polymyxin ( which kills most Gram-negative bacteria, including " Pseudomonas aeruginosa " ) and bacitracin ( which kills most Gram-positive bacteria and " Neisseria " species ).
40.
Fluoroquinolones, sodium sulfacetamide, or trimethoprim / polymyxin may be used, typically for 7 10 days . Cases of meningococcal conjunctivitis can also be treated with systemic penicillin, as long as the strain is sensitive to penicillin.