Individuals with familial adenomatous polyposis ( FAP ), a syndrome of early-onset colonic polyps and adenocarcinoma, frequently develop hepatoblastomas.
32.
Other conditions consisting of multiple hamartomatous polyps of the digestive tract include Peutz-Jeghers syndrome, juvenile polyposis, and Cowden disease.
33.
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli ( APC ) protein-binding EB1 gene family.
34.
He is a co-author of the Bethesda Guidelines for the diagnosis of Hereditary non-polyposis colorectal cancer ( HNPCC ).
35.
One relatively rare form of the disease ( familial polyposis ) is strongly genetic, but many cases of colorectal cancers have inherited components.
36.
Examples of proteins that contain armadillo repeats include ?-importin, plakoglobin, adenomatous polyposis coli ( APC ), and many others.
37.
The serrated polyposis syndrome ( SPS ) is a relatively rare condition characterized by multiple and / or large serrated polyps of the colon.
38.
Each girl had a 50 percent chance of inheriting the familial polyposis gene, and each has been examined regularly for signs of the disease.
39.
From 1996 to 1998, Searle, the maker of Celebrex at that time, conducted a study with patients who had familial adenomatous polyposis.
40.
Multiple adenomatous polyps often result from familial polyposis coli or familial adenomatous polyposis, a condition that carries a very high risk of colon cancer.