Before mitosis almost all cyclin B1 in the cell is located in the cytoplasm, but in late prophase it relocates to the nucleus.
32.
RPA also binds to ssDNA during the initial phase of homologous recombination, an important process in DNA repair and prophase I of meiosis.
33.
Synapsis and recombination during meiotic prophase I in these unisexual females is thought to ordinarily occur between identical sister chromosomes and occasionally between homologous chromosomes.
34.
This " tripartite structure " is seen during the pachytene stage of the first meiotic prophase, both in males and in females during gametogenesis.
35.
During prophase, the steep gradient in RanGTP-RanGDP ratio at the nuclear pores breaks down as the nuclear envelope becomes leaky and disassembles.
36.
Instead, the microtubules of the mitotic spindle aggregate on the nuclear surface and are reoriented to form the spindle at the end of prophase.
37.
Specifically, Aurora B localizes to the chromosomes in prophase, the centromere in prometaphase and metaphase, and the central mitotic spindle in anaphase.
38.
With the onset of prophase, the motor protein, dynein, provides the majority of the force required to pull the two centrosomes apart.
39.
In crossing-over, a Spo11 enzyme makes staggered nicks in a pair of sister chromatid strands ( in a tetrad organization of prophase ).
40.
However, primary oocytes are arrested in prophase 1 of the first meiosis and remain in that arrested stage until puberty begins in the female adult.
