"' Aminocyclopropane-1-carboxylic acid synthase "'( ACC synthase, ACS ) ( ) is an enzyme that cofactor pyridoxal phosphate ( PLP, the active form of vitamin B6 ) for stabilization.
32.
Rather, the tRNA-bound seryl residue is converted to a selenocysteine residue by the pyridoxal phosphate-containing enzyme SBP2 for eukaryotic mSelB / eEFSec ) which bind to the corresponding RNA secondary structures formed by the SECIS elements in selenoprotein mRNAs.
33.
These include ATP synthase ( ? and ? subunits ), myosin, transducin, helicases, kinases, AAA proteins, G-proteins, RecA, protein tyrosine phosphatases ( see below ) and pyridoxal phosphate utilizing enzymes such as cysteine synthase.
34.
The P-protein is a pyridoxal phosphate-dependent glycine decarboxylase that transfers the methylamine moiety of glycine to one of the thiol groups in the lipoyl component of H-protein, a hydrogen-carrier protein and the second component of the complex.
35.
In the 1950s, while studying Enterococcus, a lactic acid bacteria found in the gastrointestinal tract, Gunsalus discovered various forms of lipoic acid, as well as pyridoxal phosphate, an active form of vitamin B 6, and was granted a patent in 1962 on lipoic acid.
36.
S-Adenosylethionine can bind as a substrate for ACC synthase ( with higher affinity than SAM ) and therefore inhibit any reaction with SAM . ACC Synthase is also competitively inhibited by aminoethoxyvinylglycine ( AVG ) and aminooxyacetic acid ( AOA ), inhibitors to many pyridoxal phosphate-mediated enzymic reactions.
37.
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components : P protein ( a pyridoxal phosphate-dependent glycine decarboxylase ), H protein ( a lipoic acid-containing protein ), T protein ( a tetrahydrofolate-requiring enzyme ), and L protein ( a lipoamide dehydrogenase ).
