One proposed mechanism involves the accumulation of myelin debris at the axon, suggesting that the inflammatory environment may be conducive to remyelination, as does the release of growth factors by inflammatory cells and activated microglia.
32.
There are a variety of types of these receptors, but a majority of them tend to increase, especially in the chronic stages of demyelinating diseases, suggesting that they may be involved with remyelination failure.
33.
Recent work on this cell has provided needed insight on the rolling processes : the process of demyelination, the spontaneous ability of the CNS to regenerate myelin, and the inevitable failure of " remyelination ".
34.
Repair processes, called remyelination, also play an important role in MS . Remyelination is one of the reasons why, especially in early phases of the disease, symptoms tend to decrease or disappear temporarily.
35.
Repair processes, called remyelination, also play an important role in MS . Remyelination is one of the reasons why, especially in early phases of the disease, symptoms tend to decrease or disappear temporarily.
36.
Glial cells are important in hormonal and neuroendocrine function in the central nervous system and have an active role in sleep, cognition, synaptic function and plasticity, and promote remyelination and regeneration of injured nervous tissue.
37.
Even if a viable source of OPCS were found, identifying and monitoring the outcome of remyelination remains difficult, though multimodal measures of conduction velocity and emerging magnetic resonance imaging techniques offer improved sensitivity versus other imaging methods.
38.
Recently, she has been funded by NIH-NINDS and Jacob's Cure to study the potential of subpopulations of stem cells to promote remyelination and phenotypic rescue in animal models of white matter disease, including the Canavan mouse model.
39.
Distinct patterns of diffusivity in MS lesions suggest that axonal loss dominates in the T1 hypointense core and that the effects of de / remyelination may be better detected in the " T2-rim ", where there is relative preservation of structural integrity.
40.
These scars ( sclerae ) are the known plaques or lesions usually reported in MS . A repair process, called remyelination, takes place in early phases of the disease, but the oligodendrocytes are unable to completely rebuild the cell's myelin sheath.
