D-ACTX-Ar1a causes a prolongation of action potential duration, accompanied by spontaneous repetitive firing, but does not depolarize the resting membrane potential.
32.
KCNA5 are also key players in pulmonary vascular function, where they play a role in setting the resting membrane potential and its involvement during hypoxic pulmonary vasoconstriction.
33.
Inwardly rectifying potassium channels, such as K ir 2.6, maintain resting membrane potential in excitable cells and aid in repolarization of cells following depolarization.
34.
This change in the resting membrane potential at seizure foci could cause spontaneous opening of voltage-activated calcium channels, leading to glutamic acid release and further depolarization.
35.
After an action potential travels down the axon of a neuron, the resting membrane potential of the axon must be restored before another action potential can travel the axon.
36.
Both the inactivation of the sodium ion channels and the opening of the potassium ion channels act to repolarize the cell's membrane potential back to its resting membrane potential.
37.
To simplify the description of the ionic basis of the resting membrane potential, it is most useful to consider only one ionic species at first, and consider the others later.
38.
In the nervous system, voltage-gated K + channels control the excitability of nerves and muscles by controlling the resting membrane potential and by repolarizing the membrane during action potentials.
39.
It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization, thereby contributing to the regulation of insulin secretion.
40.
Opening of the BK channel leads to an increased K +-efflux which hyperpolarizes the resting membrane potential, reducing the excitability of the cell in which the BK-channel is expressed.