| 31. | Lewy bodies may be found in the brainstem ( within the Substantia Nigra ) or within the cortex.
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| 32. | Another important input comes from the substantia nigra, pars reticulata, a component of the basal ganglia.
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| 33. | Such degradation can occur in the substantia nigra where decreased dopamine production results in a loss of function.
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| 34. | Disorders in energy creation by mitochondria can cause cellular degeneration, like those seen in the substantia nigra.
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| 35. | However, with this treatment, the number of substantia nigra neurons decrease so it becomes less efficient.
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| 36. | This disease is caused by cells being destroyed in the part of the brainstem called the substantia nigra.
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| 37. | The locomotor enhancing properties of cocaine may be attributable to its enhancement of dopaminergic transmission from the substantia nigra.
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| 38. | Purkyn was also the first to describe and illustrate in 1838 the intracytoplasmic pigment neuromelanin in the substantia nigra.
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| 39. | Parkinson's disease is a neurodegenerative disease affecting the substantia nigra, a component of the basal ganglia.
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| 40. | In vivo the direct administration of neurturin into substantia nigra of mice models also shows mature DA neuron protection.
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