| 31. | Research and brain autopsies have implicated both dopaminergic system and iron insufficiency in the substantia nigra.
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| 32. | As with dopaminergic neurons in the substantia nigra, neurons in the locus caeruleus tend to be melanin-pigmented.
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| 33. | GNMT is also expressed in various neurons presented in the cerebral cortex, hippocampus, substantia nigra and cerebellum.
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| 34. | Disorders in energy creation by mitochondria can cause cellular degeneration, like those seen in the substantia nigra.
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| 35. | Such degradation can occur in the substantia nigra where decreased dopamine production results in a loss of function.
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| 36. | Lewy bodies may be found in the brainstem ( within the Substantia Nigra ) or within the cortex.
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| 37. | Parkinson's disease results from a progressive loss of cells in the brain's motor control center, the substantia nigra.
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| 38. | Parkinson's disease occurs when brain cells of the substantia nigra, a small black area of the brain, die.
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| 39. | This disease is caused by cells being destroyed in the part of the brainstem called the substantia nigra.
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| 40. | In addition, TRPC4 mRNA is present in midbrain dopaminergic neurons in the ventral tegmental area and the substantia nigra.
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