The ectodomain then migrates across the synaptic cleft and binds to and activates a member of the EGF-receptor family on the postsynaptic membrane.
32.
Neurotransmitters must be present in the axon terminal and then exocytosed into the synaptic cleft in order to propagate the signal to the next neuron.
33.
It should also be noted that this does not exclude full vesicle fusion, but only states that both mechanisms may operate in synaptic clefts.
34.
This enzyme is abundant in the synaptic cleft, and its role in rapidly clearing free acetylcholine from the synapse is essential for proper muscle function.
35.
The first cell ( the presynaptic cell ) sends a neurotransmitter across the synaptic cleft where it activates the second cell ( the postsynaptic cell ).
36.
During neurotransmission, the pre-synaptic neuron releases neurotransmitters into the synaptic cleft which bind to cognate receptors expressed on the post-synaptic neuron.
37.
In neurons with TAAR1, TAAR1 agonists increase the concentrations of the associated monoamines in the synaptic cleft, thereby increasing post-synaptic receptor binding.
38.
Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay.
39.
This increases the availability of 5-HT in the synaptic cleft . The main parameters to consider in choosing an antidepressant are side effects and safety.
40.
Several diseases and problems can be caused by the inability of enzymes to clear away the neurotransmitters from the synaptic cleft leading to continued action potential propagation.
