After reaching a 16-cell stage, the totipotent cells of the morula differentiate into cells that will eventually become either the blastocyst's Inner cell mass or the outer trophoblasts.
32.
Cells resembling 2-cell-stage mouse embryos ( totipotent cells ) can be induced in vitro through downregulation of the chromatin-assembly activity of CAF-1 in embryonic stem cells.
33.
The cells may also be " totipotent, " meaning they can form every one of the body's cell types, but the experiment to prove this point would be unethical.
34.
It would be unethical to perform such an experiment on people but if it could be done, it seems likely that the human embryonic cells cultured by the researchers would also prove to be totipotent.
35.
A totipotent cell, capable of forming all human tissues, would be tantamount to an embryo, but a pluripotent cell, able to make many but not all tissues, would be something less.
36.
Is there a way to make adult stem cells totipotent and therefore provide an alternative non-controversial method of making totipotent stem cells ? talk ) 16 : 48, 18 November 2013 ( UTC)
37.
Is there a way to make adult stem cells totipotent and therefore provide an alternative non-controversial method of making totipotent stem cells ? talk ) 16 : 48, 18 November 2013 ( UTC)
38.
In embryonic development, totipotent cells ( ostensibly organisms ) divide into pluripotent cells ( ostensibly non-organisms ), which in turn divide into cells that are " committed " to become specific tissues.
39.
"' Callus "', or dedifferentiated cells, are somatic cells that undergo dedifferentiation to give rise to totipotent embryogenic cells, which temporarily gains the ability to proliferate and / or regenerate an embryo.
40.
This result challenges the terminal nature of cellular differentiation and the integrity of lineage commitment; and implies that with the proper tools, " all " cells are totipotent and may form all kinds of tissue.
