| 31. | For example, troponin T mutations were originally associated with a 50 % mortality before the age of 40.
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| 32. | Troponin measurement has largely replaced this in many hospitals, although some centers still rely on CK-MB.
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| 33. | Thus, the tropomyosin-troponin complex again covers the binding sites on the actin filaments and contraction ceases.
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| 34. | Intracellular calcium concentration drops and troponin complex returns over the active site of the actin filament, ending contraction.
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| 35. | Other causes of raised Troponin I include chronic renal failure, heart failure, subarachnoid haemorrhage and pulmonary embolus.
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| 36. | It is the tropomyosin-binding and thin filament anchoring subunit of the troponin complex in cardiac muscle cells.
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| 37. | Troponin modulators could also be used to reverse the impact of cardiomyopathy-causing mutations in the thin filament.
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| 38. | Tests have shown that the cardiac marker Troponin I can be measured in blood plasma in around five minutes.
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| 39. | Views on the actual amount of calcium that binds to troponin vary from expert to expert and source to source.
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| 40. | JNJ460 also resulted in more structural proteins associated with intercellular growth, such as actin, myosin, and troponin.
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