Hemocyanin is homologous to the phenol oxidases ( e . g . tyrosinase ) since both enzymes share type 3 Cu active site coordination.
32.
Another chemical of interest found in " P . indusiatus " is hydroxymethylfurfural, which has attracted attention as a tyrosinase inhibitor.
33.
This cysteine-histidine cross-linking may further restrain the enzyme active site from assuming the bidentate coordination complex readily formed in tyrosinase.
34.
This is due to their inability to produce normal tyrosinase, a trait they share with albinos, according to zoo veterinarian David Taylor.
35.
In the opinion of the scientists, it may exist additional physiological functions for melanin / functional tyrosinase that are not involved with pigmentation.
36.
They also identified tyrosinase-related protein 1 ( TYRP1 ) as a major determinant of blond hair among the Melanesian of Solomon Islands.
37.
Studies in 2012 showed that naturally blond hair of Melanesians is caused by a recessive mutation in tyrosinase-related protein 1 ( TYRP1 ).
38.
The enzyme tyrosinase catalyzes the oxidation of L-DOPA to the reactive intermediate dopaquinone, which reacts further, eventually leading to melanin oligomers.
39.
Gray hair is probably caused by lack of a protein called tyrosinase, maybe because the gene for that substance gets turned off, he said.
40.
When the enzyme tyrosinase, activated by sunlight coming into contact with tyrosin, the process of melanin formation through biochemical chain reactions and polymerisations starts.
