Epothilone B has proven to contain potent " in vivo " anticancer activities at tolerate dose levels in several human xenograft models.
32.
In a rat xenograft model, cilengitide was able to potentiate the cytotoxic effects of radiation when cilengitide was administered prior to radiation therapy.
33.
Using a human fetal prostate xenograft model, researchers studied the effects of early exposure to estrogen with and without secondary estrogen and testosterone treatment.
34.
If hyperacute and acute vascular rejection are avoided accommodation is possible, which is the survival of the xenograft despite the presence of circulating XNAs.
35.
EC145 was found to produce marked anti-tumor effect against well-established, subcutaneous FR-positive tumor xenografts using well tolerated regimens.
36.
In 1976 Shiley Laboratory in California began to manufacture and to distribute worldwide this valve under the name of'Ionescu Shiley Pericardial Xenograft '.
37.
BIBW 2992 inhibits survival of cancer cell lines and induces tumour regression in xenograft and transgenic lung cancer models, with superior activity over erlotinib.
38.
If hyperacute rejection can reliably be overcome, the next hurdle may be delayed xenograft rejection, or DXR, which occurs several days following transplant.
39.
As serious as these concerns may be, objections regarding cross-species transplants, or xenografts, are not rooted in public health fears alone.
40.
Currently, some of the only xenograft experiments are being carried out by a Boston biotech company, Diacrine Inc ., in collaboration with Genzyme.
