Perhaps the most powerful testament to the healing power of the mind is the placebo, a look-alike but inactive remedy that, on average, benefits about one-third of those who receive it when active treatments are tested in clinical trials.
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A . Idiopathic scoliosis, a sideways curve of the spine of unknown cause in adolescence, is now believed to require active treatment in only about 10 percent of cases, according to " The Merck Manual of Diagnosis and Therapy ."
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In it, Beecher, who died in 1976, reviewed about a dozen studies that compared placebos to active treatments and concluded that placebos had medical effects . " He came up with the magical 35 percent number that has entered placebo mythology,"
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In 1863, Austin Flint ( 1812 1886 ) in his report of the first-ever trial that directly compared the efficacy of a placebo treatment with that of an active treatment, spoke of " the natural history of [ an untreated ] disease ".
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In a randomized, placebo-controlled trial alcohol-dependent subjects taking flumazenil / gabapentin had more abstinent days and time to first heavy drinking if they had high alcohol withdrawal symptoms prior to treatment, whereas the patients with low withdrawal symptoms actually did worse with active treatment.
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This hospital has a TB clinic for outdoor patients, but of the 2, 750 new patients registered in the last year ( along with an older backlog of 2, 000 inadequately treated patients ), officials admit that only 30 per cent are under active treatment.
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In the three runs of the trial, mortality and severe adverse events in the active treatment group were consistent with their occurrence in the control group . ( 4, 16-18 ) This indicated that transcranial light therapy using the conditions of the NEST trials was safe.
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Active treatment can be defined as the individualized implementation of a program of training, treatment, health, and related services directed toward the rehabilitation of the behaviors necessary for the MR / DD individual to function within the general scope of their being and independence as well as possible.
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Dr . E . Roy John, a professor at New York University's School of Medicine and director of the Brain Research Laboratories there, who was scheduled to deliver two papers, said he had been particularly interested in sessions on bringing people out of comas through more active treatment.
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The Cochrane review of two studies on this subject concluded that there was no statistically significant evidence that interventions were associated with a more rapid resolution of symptoms; in these studies women tended to have improvements in pain and other symptoms over time whether or not they received active treatment.
