Mountain View-based Scios Nova Inc . said its treatment for acute kidney failure, Auriculin, failed to show benefits for most patients treated during 27 months of clinical study.
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A serious complication of E . coli, however is hemolytic uremic syndrome, a condition in which sudden, rapid destruction of red blood cells causes acute kidney failure, said Fannin.
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The cells also manufacture cytokines, proteins that signal the immune system and help avert deadly bacterial infections, which are the primary cause of death among people who experience acute kidney failure.
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Within a few days, five company employees were found to be infected with O157 and one 56-year-old employee died of acute kidney failure brought on by the bacteria.
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There has been a case of nephrotoxin poisoning, including delayed onset acute kidney failure associated with the ingestion of this mushroom, in a 66-year-old man with diabetes.
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Scios Nova Inc . saw its shares plunge 46 percent to 3 1 / 4 in May after the company said its Auriculin treatment for acute kidney failure worked in far fewer patients than expected.
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Though most reports describe IgA nephropathy as having an indolent evolution towards either healing or renal damage, a more aggressive course is occasionally seen associated with extensive crescents, and presenting as acute kidney failure.
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Since the major cause of acute kidney failure in this setting is uric acid build-up, therapy consists of rasburicase to wash out excessive uric acid crystals as well as a loop diuretic and fluids.
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One presumed factor arising from excessive consumption of coconut water is an over-abundance of potassium in the blood ( hyperkalemia ), inducing acute kidney failure, heart arrhythmia, loss of consciousness and eventually death.
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It is frequently associated with obstetric catastrophes such as abruptio placentae and septic shock, and is three times more common in developing nations versus industrialized nations ( 2 % versus 6 % in causes of acute kidney failure ).
