Minnich et al . dosed mongrel dogs subcutaneously with aminopterin and folic acid simultaneously to test whether folic acid can rescue animals from the lethality and toxicity of aminopterin Dogs were given 0.020, 0.046, 0.044 escalated to 0.088, and 0.097 mg / kg aminopterin each day for 7 to 12 days . Folic acid was given in a weight ratio to aminopterin of 200 : 1 to 800 : 1.
42.
Minnich et al . dosed mongrel dogs subcutaneously with aminopterin and folic acid simultaneously to test whether folic acid can rescue animals from the lethality and toxicity of aminopterin Dogs were given 0.020, 0.046, 0.044 escalated to 0.088, and 0.097 mg / kg aminopterin each day for 7 to 12 days . Folic acid was given in a weight ratio to aminopterin of 200 : 1 to 800 : 1.
43.
Minnich et al . dosed mongrel dogs subcutaneously with aminopterin and folic acid simultaneously to test whether folic acid can rescue animals from the lethality and toxicity of aminopterin Dogs were given 0.020, 0.046, 0.044 escalated to 0.088, and 0.097 mg / kg aminopterin each day for 7 to 12 days . Folic acid was given in a weight ratio to aminopterin of 200 : 1 to 800 : 1.
44.
Minnich et al . dosed mongrel dogs subcutaneously with aminopterin and folic acid simultaneously to test whether folic acid can rescue animals from the lethality and toxicity of aminopterin Dogs were given 0.020, 0.046, 0.044 escalated to 0.088, and 0.097 mg / kg aminopterin each day for 7 to 12 days . Folic acid was given in a weight ratio to aminopterin of 200 : 1 to 800 : 1.
