Improper progression through the centrosome cycle can lead to incorrect numbers of centrosomes and aneuploidy, which could eventually lead to cancer.
42.
:See biological sex, gender, sex chromosomes, XY sex-determination system, aneuploidy, sex differences in humans.
43.
In particular, risk of aneuploidy is increased by tobacco smoking, and occupational exposure to benzene, insecticides, and perfluorinated compounds.
44.
Meiotic errors can lead to aneuploidy in the polar bodies, which, in the majority of cases, produces an aneuploid zygote.
45.
Failure to establish cohesion correctly or inappropriate loss of cohesion can lead to missegregation of chromosomes during mitosis, which results in aneuploidy.
46.
The multipolar metaphase-anaphase transition occurs through an incomplete separase cycle that results in frequent nondisjunction events which amplify aneuploidy in cancer cells.
47.
Some researchers believe that cancer may be caused by aneuploidy ( numerical and structural abnormalities in chromosomes ) rather than by mutations or epimutations.
48.
Chromosome segregation errors can lead to DNA damage and micronuclei generally occurs concurrently with aneuploidy and aneuploidy cells are controlled by mechanisms involving p53.
49.
Chromosome segregation errors can lead to DNA damage and micronuclei generally occurs concurrently with aneuploidy and aneuploidy cells are controlled by mechanisms involving p53.
50.
It can be used for gene mapping, detecting aneuploidy, locating tumours etc . The multicolour probes attach to a certain DNA fragment.
